A woman has died and five others have been injured after multiple vehicles were involved in a crash east of Melbourne.
Police believe a truck and three cars were involved in the collision in the west-bound lanes of the Princes Freeway near the Bona Vista Road exit in Darnum about 8.40am.
A front seat passenger of a bronze Jeep, a 30-year-old Warragul woman, died at the scene.
The driver of that car, a 32-year-old Warragul woman, was airlifted to the Royal Melbourne Hospital with life-threatening-injuries.
The backseat passenger, a 14-year-old Warragul girl, was airlifted to the Royal Children's Hospital with serious injuries.
The occupants of a white Mitsubishi, a 53-year-old Yarragon man and a teenage boy from Yarragon, were treated by paramedics.
The sole driver of a silver Mazda, a 21-year-old Tooradin woman, was transported to hospital with non-life-threatening injuries.
The truck driver, a 61-year-old Trafalgar man, is assisting police investigating the crash.
Victoria Police Detective Sergeant Darryl Out described the scene as "horrific".
"Everybody that would have seen that would have been just absolutely devastated by it," he said.
"The 14-year-old child was very, very traumatised by it."
About 9.45am, an hour after the first crash, a second collision occurred on the outbound lanes of the Princes Freeway at Nilma, just hundreds of metres away.
Two people were taken to Latrobe Regional Hospital.
The crashes come after a horror weekend on Victorian roads.
Three teenagers and a woman in her 30s were killed in a crash in Bochara on Saturday morning and a 17-year-old girl was left in a critical condition.
Two people were killed after a car hit a powerpole in Thomastown yesterday morning.
A 53-year-old woman also died last night after she was the victim of an alleged hit-run in Point Cook on Friday night.
Sign up here to receive our daily newsletters and breaking news alerts, sent straight to your inbox.